Expression of Bovine Viral Diarrhoea Virus E2 Gene in HeLa Cell Line

Analysis of variation of bovine viral diarrhoea virus E2 sequence following transplacental infection of cattle.

The genetic and antigenic diversity observed in field isolates of bovine viral diarrhoea virus (BVDV) is thought to occur during acute infection because of the genetic stability observed in BVDV throughout the lifetime of persistently infected (PI) cattle. In this study, 15 cows in early pregnancy were inoculated with identical challenge doses obtained from a single infectious inoculum of the v...

Gene expression changes in MDBK cells infected with genotype 2 bovine viral diarrhoea virus.

Bovine viral diarrhoea viruses (BVDVs) are ubiquitous viral pathogens of cattle. These viruses exist as one of two biotypes, cytopathic and noncytopathic, based on the ability to induce cytopathic effect in cell culture. The noncytopathic biotypes are able to establish inapparent, persistent infections in both cell culture and in bovine foetuses of less than 150 days gestation. Interactions wit...

The occurrence of bovine virus diarrhoea/muscosal disease in Iran

Expression, purification and crystallization of the ectodomain of the envelope glycoprotein E2 from Bovine viral diarrhoea virus.

Bovine viral diarrhoea virus (BVDV) is an economically important animal pathogen which is closely related to Hepatitis C virus. Of the structural proteins, the envelope glycoprotein E2 of BVDV is the major antigen which induces neutralizing antibodies; thus, BVDV E2 is considered as an ideal target for use in subunit vaccines. Here, the expression, purification of wild-type and mutant forms of ...

Prevalence of bovine viral diarrhoea virus antibodies in India.

A study was undertaken regarding the prevalence of bovine viral diarrhoea virus (BVDV) antibodies in bovine sera which tested negative for rinderpest and peste des petits ruminants virus antibodies. The samples were collected between January 1996 and December 1997. A total of 439 samples (327 cattle and 112 buffalo from 17 states of India) were tested using a commercial enzyme-linked immunosorb...